Sulforaphane
Commonly used for
InflammationHealthy AgingMetabolic Health
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The cheapest product is usually low quality, but more expensive doesn’t always mean better.
Wellness uses
Detox support
This is anecdotal, and there isn't strong clinical evidence that it works for everyone.
What is it? / Overview
Sulforaphane activates the Nrf2 pathway increasing production of the body's own antioxidant and detoxification enzymes rather than acting as a direct antioxidant. Human studies suggest benefits for oxidative stress and metabolic health but evidence for disease prevention remains preliminary.
How is it used? / Administration
Form: Stabilized sulforaphane or glucoraphanin + active myrosinase (broccoli sprout extract)
Typical dose studied: 20–40 mg sulforaphane/day equivalent
Timing: With meals
Fresh broccoli sprouts provide one of the richest natural sources. Products with both glucoraphanin and active myrosinase produce higher sulforaphane levels.
How well does it work? / Evidence
? Emerging / limited evidence
Who should avoid it?
Interacts with: Theoretical CYP enzyme interaction — limited clinical significance
Already taking it? Choose products with active myrosinase or stabilized sulforaphane for reliable bioavailability.
Research & references
Fahey JW et al. (2013). Health span extension through green chemoprevention. Virtual Mentor. Egner PA et al. (2011). Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China. Cancer Prev Res (Phila).
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