Stinging Nettle Root
Commonly used for
Men's Health
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What is it? / Overview
Nettle root constituents are proposed to bind sex-hormone-binding globulin and weakly inhibit aromatase and 5-alpha-reductase, along with anti-inflammatory effects on prostate tissue -- human efficacy is modest and inconsistent, and it's not endorsed in EAU/AUA guideline algorithms.
How is it used? / Administration
Form: Urtica dioica root extract -- distinct from nettle leaf, which is used for allergies/joint discomfort
Typical dose studied: ~300-600 mg/day root extract, often combined with saw palmetto or pygeum
Timing: With food
This entry is specifically nettle ROOT for BPH/urinary symptoms -- nettle LEAF (allergic rhinitis, joint discomfort) is a distinct traditional use with different active constituents and isn't covered here.
How well does it work? / Evidence
? Emerging / limited evidence
Who should avoid it?
Interacts with: Antihypertensives, diuretics, antidiabetic agents -- mild theoretical additive effects reported
Already taking it? Reasonable to continue -- modest, less consistent effect than pygeum, and much of the positive data comes from combination products rather than nettle root alone.
Research & references
Antoniou V et al. (2023). Role of Phytotherapy in the Management of BPH: A Summary of the Literature. Journal of Clinical Medicine. Allkanjari O, Vitalone A (2015). What Do We Know About Phytotherapy of Benign Prostatic Hyperplasia? Life Sciences.
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