Resveratrol
Commonly used for
Healthy AgingHeart HealthMetabolic Health
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What is it? / Overview
Wellness uses some people report: anti-aging and longevity. This is anecdotal, and there isn't strong clinical evidence that it works for everyone. Resveratrol is a polyphenol found in grapes and berries that activates pathways involved in mitochondrial function and cellular stress responses. Human studies show modest improvements in insulin sensitivity and vascular function though anti-aging effects remain inconclusive.
How is it used? / Administration
Form: Trans-resveratrol (≥98% purity)
Typical dose studied: 150–500 mg/day
Timing: With fat-containing meal
Use trans-resveratrol. Human benefits considerably smaller than animal model data. Often overhyped relative to current evidence strength.
How well does it work? / Evidence
? Emerging / limited evidence
Who should avoid it?
Avoid with: Bleeding disorder / Coagulopathy
Interacts with: Anticoagulants; Antiplatelet medications
Already taking it? Benefits generally modest. Reassess after 2–3 months.
Research & references
Liu K et al. (2014). Resveratrol and glucose control meta-analysis. AJCN. Hausenblas HA et al. (2015). Resveratrol in type 2 diabetes meta-analysis. Molecular Nutrition & Food Research. Berman AY et al. (2017). Therapeutic potential of resveratrol review. NPJ Precision Oncology.
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