NAC (N-Acetylcysteine)
Commonly used for
EnergyHealthy AgingImmune Support
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Wellness uses
Hangover recovery and liver detox, endometriosis support
This is anecdotal, and there isn't strong clinical evidence that it works for everyone.
What is it? / Overview
NAC replenishes glutathione one of the body's primary antioxidants and also helps thin respiratory mucus. It has established medical uses and growing evidence for several chronic health conditions.
How is it used? / Administration
Form: N-acetyl-L-cysteine
Typical dose studied: 600–1,800 mg/day in divided doses
Timing: With or without food
Characteristic sulfur odor is normal. Well-established safety profile.
How well does it work? / Evidence
~ Moderate evidence
Who should avoid it?
Avoid with: Peptic ulcer disease
Interacts with: Nitroglycerin — may increase hypotension and headaches
Already taking it? Assess ongoing need after 2–3 months.
Research & references
Samuni Y et al. (2013). The chemistry and biological activities of N-acetylcysteine. Biochim Biophys Acta.
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