Myo-Inositol
Commonly used for
Weight LossMetabolic HealthMenstrual Health
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Wellness uses
PCOS support, panic and anxiety support, and thyroid support
This is anecdotal, and there isn't strong clinical evidence that it works for everyone.
What is it? / Overview
Myo-inositol functions as an intracellular signaling molecule involved in insulin action. In women with PCOS it can improve insulin sensitivity, menstrual regularity, and ovulation with a favorable safety profile.
How is it used? / Administration
Form: Myo-inositol powder
Typical dose studied: 2 g twice daily (4 g/day total)
Timing: Morning and evening
Often combined with folate. The 40:1 ratio of myo-inositol to D-chiro-inositol has the strongest evidence.
How well does it work? / Evidence
~ Moderate evidence
Who should avoid it?
Interacts with: Diabetes medications — monitor glucose
Already taking it? Reassess after approximately 3 months.
Research & references
Unfer V et al. (2017). Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials. Endocr Connect. Facchinetti F et al. (2020). Myo-inositol in PCOS meta-analysis. Gynecological Endocrinology. International Evidence-based Guideline for PCOS Assessment and Management (2023).
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