L-Glutamine
Commonly used for
Athletic Performance
Where to Buy
Our experts personally review each product we recommend for quality and cost effectiveness.
The cheapest product is usually low quality, but more expensive doesn’t always mean better.
The cheapest product is usually low quality, but more expensive doesn’t always mean better.
Wellness uses
Leaky gut support
This is anecdotal, and there isn't strong clinical evidence that it works for everyone.
What is it? / Overview
Glutamine is a fuel source for intestinal and immune cells and becomes conditionally essential during severe physical stress, illness, or gut-lining disruption. Its role as intestinal-cell fuel is a mechanistic rationale, not proven benefit for nonspecific digestive symptoms or routine training recovery.
How is it used? / Administration
Form: L-Glutamine powder or capsules
Typical dose studied: 5–10 g/day
Timing: Post-workout or on an empty stomach
How well does it work? / Evidence
? Emerging / limited evidence
Who should avoid it?
Avoid with: Cancer — active or within past 12 months; End-stage liver disease / Cirrhosis
Already taking it? Evidence for routine athletic or general gut-support use is limited and context-dependent — benefit is best established in specific illness/injury/severe-stress settings, not nonspecific digestive symptoms.
Research & references
Legault Z et al. (2015). The Influence of Oral L-Glutamine Supplementation on Muscle Strength Recovery and Soreness Following Unilateral Knee Extension Eccentric Exercise. Int J Sport Nutr Exerc Metab.
Disclosure: Knozela is a participant in the Amazon Associates affiliate program. Some "Where to buy" links on this page are affiliate links -- if you make a purchase through them, Knozela may earn a commission at no additional cost to you.