CoQ10 (Ubiquinol)
Commonly used for
EnergyHealthy AgingHeart Health
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What is it? / Overview
CoQ10 is involved in cellular energy production and acts as an antioxidant. Levels decline with age and statin therapy making supplementation helpful for some people experiencing statin-related muscle symptoms or fatigue.
How is it used? / Administration
Form: Ubiquinol preferred for older adults; ubiquinone also effective
Typical dose studied: 100–200 mg/day
Timing: With fat-containing meal
Best absorbed with dietary fat. Ubiquinol may be better for adults over 40.
How well does it work? / Evidence
~ Moderate evidence
Who should avoid it?
Avoid with: Hypotension / Low blood pressure
Interacts with: Warfarin — may reduce anticoagulant effect
Already taking it? Allow 8–12 weeks to evaluate benefit.
Research & references
Banach M et al. CoQ10 and Statin Myopathy. NIH Office of Dietary Supplements. AHA reviews on CoQ10.
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