Chromium

Commonly used for

Metabolic HealthBlood Sugar Control

What is it? / Overview

Chromium enhances insulin signaling and plays a role in carbohydrate metabolism. Although supplementation may produce small improvements in blood glucose in some people with type 2 diabetes, evidence is inconsistent and it is not recommended as a primary diabetes treatment.

How is it used? / Administration

Form: Chromium picolinate (most studied); chromium nicotinate alternative

Typical dose studied: 200–1,000 mcg/day (200–400 mcg/day most commonly studied)

Timing: With meals

True chromium deficiency is rare. Routine supplementation for weight loss or bodybuilding is NOT supported by current evidence.

How well does it work? / Evidence

? Emerging / limited evidence

Who should avoid it?

Avoid with: Chronic kidney disease (Stage 3, 4, or 5) — NOT on dialysis; Dialysis (Hemodialysis or Peritoneal Dialysis); End-stage liver disease / Cirrhosis

Interacts with: Insulin; Sulfonylureas; Metformin — monitor blood glucose; Levothyroxine — separate by 3–4 hrs

Already taking it? Monitor blood glucose if used alongside diabetes medications.

Research & references

Suksomboon N et al. (2014). Chromium and diabetes systematic review and meta-analysis. Journal of Clinical Pharmacy and Therapeutics. Balk EM et al. (2007). Chromium and glucose/lipid metabolism systematic review. Diabetes Care. NIH Office of Dietary Supplements: Chromium Fact Sheet.