Black Seed (Nigella sativa)
Commonly used for
InflammationMetabolic HealthMetabolic Syndrome
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The cheapest product is usually low quality, but more expensive doesn’t always mean better.
What is it? / Overview
Black seed contains thymoquinone, a bioactive compound with antioxidant and anti-inflammatory effects. Clinical trials suggest modest improvements in blood glucose, lipid levels, and inflammatory markers, though it should be considered an adjunct rather than a primary therapy.
How is it used? / Administration
Form: Standardized extract or cold-pressed oil, standardized for thymoquinone where possible
Typical dose studied: 500–2,000 mg/day seed extract or 2.5–5 mL/day oil
Timing: With meals
Choose products standardized for thymoquinone content. Evidence strongest for metabolic and inflammatory outcomes. Avoid medicinal doses in pregnancy.
How well does it work? / Evidence
? Emerging / limited evidence
Who should avoid it?
Interacts with: Diabetes medications; Antihypertensive medications; Anticoagulants — use caution
Already taking it? Monitor blood glucose if used alongside diabetes medications.
Research & references
Koshak AE et al. (2020). Nigella sativa pharmacological effects review. Phytotherapy Research. Heshmati J et al. (2015). Effects of black seed (Nigella sativa) on metabolic parameters in diabetes mellitus: a systematic review. Complement Ther Med.
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