Bacillus coagulans

Commonly used for
NutritionBloatingAbdominal Discomfort
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Bacillus coagulans is a spore-forming probiotic that survives stomach acid well. Certain clinically studied strains have demonstrated improvements in bloating, abdominal pain, and overall IBS symptoms, though benefits are strain-specific.
Form: Strain-specific products (MTCC 5856 or GBI-30, 6086)
Typical dose studied: 1–2 billion CFU/day, strain dependent
Timing: With meals
Clinical benefits are strain-specific. Spore-forming probiotics are generally shelf-stable.
~ Moderate evidence
Avoid with: Organ transplant (on immunosuppression)
Interacts with: Separate from antibiotics by 2–3 hours
Already taking it? Evaluate symptom improvement after 4–8 weeks.
Majeed M et al. (2016). B. coagulans MTCC 5856 for IBS pilot study. Nutrition Journal. Zhang T et al. (2022). Probiotics for IBS network meta-analysis. Frontiers in Cellular and Infection Microbiology. British Dietetic Association. (2016). Systematic review of probiotics for IBS.
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